
I work at the intersection of AI and medicine with the goal of developing trustworthy AI systems to improve healthcare. My research program spans methodological research on impactful machine learning, medical applications for predictive risk stratification, and nuanced evaluations of icnreasingly advanced AI systems.
I am an Assistant Professor at UC Berkeley and UCSF in CPH, EECS, and BAIR. Our research has been recognized with the Google Research Scholar Award, Apple Machine Learning Research Award, ML4H Best Paper, CERSI Symposium Best Poster, and several Rising Star awards. I received my PhD from MIT EECS and my joint AB/SM in Applied Math from Harvard University. Previously, I was a postdoctoral researcher at Microsoft Research New England.
Interested in joining us? Read this page for more information and check out my advising statement.
Aggregated Individual Reporting for Post-Deployment Evaluation.
Jessica Dai, Inioluwa Deborah Raji, Benjamin Recht, and Irene Y. Chen.
ICML 2026.
Falsifying Sparse Autoencoder Reasoning Features in Language Models.
George Ma, Zhongyuan Liang, Irene Y. Chen, Somayeh Sojoudi.
ICML 2026.
Access to care improves EHR reliability and clinical risk prediction model performance.
Anna Zink, Hongzhou Luan, Irene Y Chen.
Nature Health 2026.
Patient Safety Risks from AI Scribes: Signals from End-User Feedback.
Jessica Dai, Anwen Huang, Catherine Nasrallah, Rhiannon Croci, Hossein Soleimani, Sarah J Pollet, Julia Adler-Milstein, Sara G Murray, Jinoos Yazdany, and Irene Y Chen.
ML4H 2025.
A large language model-based approach to quantifying the effects of social determinants in liver transplant decisions.
Emily Robitschek, Asal Bastani, Kathryn Horwath, Savyon Sordean, Mark J. Pletcher, Jennifer C. Lai, Sergio Galletta, Elliott Ash, Jin Ge*, Irene Y Chen*.
npj Digital Medicine 2025
Best Findings Paper Award (ML4H 2024).
Leonidas H. Berry Health Equity Research Award (ACG 2024).
The evaluation illusion of large language models in medicine.
Monica Agrawal, Irene Y Chen, Freya Gulamali, and Shalmali Joshi
npj Digital Medicine 2025
Redefining Bias Audits for Generative AI in Health Care.
Irene Y Chen* and Emily Alsentzer*
NEJM AI 2025
The Data Addition Dilemma.
Judy Hanwen Shen, Inioluwa Deborah Raji, and Irene Y Chen.
MLHC 2024.
NLP for Maternal Healthcare: Perspectives and Guiding Principles in the Age of LLMs.
Maria Antoniak, Aakanksha Naik, Carla S Alvarado, Lucy Lu Wang, Irene Y Chen.
FAccT 2024.
Identifying Reasons for Contraceptive Switching from Real-World Data Using Large Language Models.
Brenda Y. Miao, Christopher YK Williams, Ebenezer Chinedu-Eneh, Travis Zack, Emily Alsentzer, Atul J. Butte, Irene Y Chen.
npj Digital Medicine.
Best Poster Award (CERSI Scientific Symposium 2024).
Machine Learning Approaches for Equitable Healthcare.
Irene Y. Chen.
PhD Thesis, Massachusetts Institute of Technology 2022.
Clustering Interval-Censored Time-Series for Disease Phenotyping.
Irene Y. Chen, Rahul G. Krishnan, David Sontag.
AAAI 2022.
Intimate Partner Violence and Injury Prediction from Radiology Reports.
Irene Y. Chen, Emily Alsentzer, Hyesun Park, Richard Thomas, Babina Gosangi, Rahul Gujrathi, Bharti Khurana.
PSB 2021.
Oral Presentation.
Ethical Machine Learning in Health Care
Irene Y. Chen, Emma Pierson, Sherri Rose, Shalmali Joshi, Kadija Ferryman, Marzyeh Ghassemi.
Annual Reviews for Biomedical Data Science 2021.
Treating health disparities with artificial intelligence
Irene Y. Chen, Shalmali Joshi, Marzyeh Ghassemi
Nature Medicine, January 2020
Robustly Extracting Medical Knowledge from EHRs: A Case Study of Learning a Health Knowledge Graph.
Irene Y. Chen, Monica Agrawal, Steven Horng, David Sontag.
PSB 2020.
Oral Presentation.
Can AI Help Reduce Disparities in General Medical and Mental Health Care?
Irene Y. Chen, Peter Szolovits, Marzyeh Ghassemi.
AMA Journal of Ethics, February 2019.
Why Is My Classifier Discriminatory?
Irene Y. Chen, Fredrik D. Johansson, David Sontag.
NeurIPS 2018.
Spotlight Presentation (top 4% of submitted papers)
Presented at WiML workshop at NeurIPS 2017.